Saturday, March 23, 2019
A Look Into the Human Genome Project :: Science Technology Genetics Papers
A Look Into the Human Genome ProjectWould people buy a rigid of books that repeated the same four letters in random enjoin page after page? Or would this information be much convenient to the public if on a computer disc? some(prenominal) people would agree with the idea that this set of books would be boring. Surprisingly, America and the tarry of the world are buying the information in this set of books. In fact, these books contain the world genome. The mapping of the genome (or writing this set of books) is a 15-year bedevil that has brought many ethical issues to at hug drugtion.History of the Human Genome ProjectThe United States incision of Energy and the National Institutes of Health joined forces in 1990 to kick sullen a 15-year effort to reach two destinationsCatalog the genes in human DNA Determine the three billion bases (the four letters in the set of books) in human DNA that encode for genes (U.S. Dept. of Energy 1998). On the international level, the Human Ge nome Organization (HUGO) was founded. Their goal is to encourage trading of investigate findings and techniques (National Reference Center 1998). From the national standpoint it brings back memories of The Manhattan Project. Internationally, this cooperation is unprecedented (Shinn 1996). onward the organization of the Human Genome Project, the Department of Energy had biologists and physicists studying the Hiroshima survivors. From this data a GenBank was made. This was the first database for DNA sequences (Gert, et al. 1996).Watson, who won the Nobel prize for his discovery of the double helix, was positive as the first director of the Human Genome Project. He appropriated three portion of his budget to ethical, legal, and social issues (ELSI) involved with the project (Shinn 1996). Even from the beginning it was pass judgment that this project could have both positive and negative outcomes.One goal to be reached after five old age was to have markers every ten centimorgans (Gert, et al. 1996). This goal was stated in 1991 and achieved in 1994 - a year forth of schedule - when a map with markers every two to five centimorgans was produce (Casey, et al. 1995). Sequencing would then follow with a focus on areas of disease and in reducing human error. The main goal for the next five years would be markers every one centimorgan (Gert, et al. 1996).Technical AspectsIdeally, the final map leave have both physical and genetic information.
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